The Local and Regional Food Systems (LRFS) Resilience Playbook is a collaborative effort between university-based researchers, LRFS leaders, and United States Department of Agriculture (USDA) experts. The Playbook is designed to support food systems leaders seeking to broaden and deepen their understanding of the distinct strengths and vulnerabilities of LRFS in times of disruption. This resource is intended to function as part primer, part inspirational guide. Beginning with the lessons learned during the COVID-19 pandemic (and the first iteration Local and Regional Food Systems Response to COVID-19 cooperative agreement that spurred this project) the project team worked to codify key principles, approaches, and insights gleaned from those experiences.